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| Host Species | Mouse |
| Species Reactivity | C. elegans, Human, Mouse, Rat, Chicken |
| Conjugate | NONE |
| Clone Number | NW0112 |
| Specificity | Rad51, a 37 kDa protein, is the human homolog of E. coli RecA protein and a member of the RAD52 epistasis group in S. cerevisiae. |
| Format | Liquid or Lyophilized |
| Purification | Affinity purified |
| Product Overview | Mouse Anti-C. elegans Rad51 (clone NW0112) Antibody is a Mouse antibody against the epitope of the Rad51. It can be used for Rad51 detection in Western Blot, Chromatin Immunoprecipitation, Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, In vitro, Immunoprecipitation, PLA, KD. |
| Target Name | Rad51 |
| Gene ID | 5888 |
| UniProt ID | Q06609 |
| Introduction | The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Application | ChIP, IF, IHC, IHC-Fr, IHC-P, IP, WB |
| Application Notes | WB: 1/100-1/3000 IF: 1/100-1/1000 IHC-P: 1/100-1/1000 |
| Shipping | Shipped on dry ice. |
| Storage | Store at 4 °C: short-term (1-2 weeks) Store at -20 °C: long-term and future use |
| Buffer | PBS |
For Research Use Only. Not For Clinical Use.Related Products
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