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| Host Species | Rabbit |
| Species Reactivity | C. elegans, Human, Mouse, Rat, Bovine, Chinese Hamster, Primat, Rhesus |
| Conjugate | NONE |
| Immunogen | Synthetic peptide in the inner region of the mouse CD11b protein. |
| Epitope | The epitope is in the AA 250-350 of ITGAM. |
| Format | Liquid or Lyophilized |
| Cellular Localization | Monocytes and granulocytes |
| Purification | Affinity purified |
| Product Overview | This product is a Rabbit antibody against the AA 250-350 of the ITGAM. It can be used for ITGAM detection in Western Blot, Simple Western, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, ISH, Dual ISH-Immunohistochemistry, Single-Cell Western. |
| Target Name | ITGAM |
| Gene ID | 3684 |
| UniProt ID | P11215 |
| Introduction | This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Application | FACS, IF, IHC, IHC-Fr, IHC-P, ISH, WB |
| Application Notes | Western Blot 2 µg/mL Simple Western 1:50 Flow Cytometry 1:10-1:1000 Immunocytochemistry/Immunofluorescence 1:200 Immunohistochemistry 1:400 Immunohistochemistry-Frozen Immunohistochemistry-Paraffin 1:400 In-situ Hybridization Dual RNAscope ISH-IHC Single Cell Western 1:10 |
| Shipping | Shipped on dry ice. |
| Storage | Store at 4 °C: short-term (1-2 weeks) Store at -20 °C: long-term and future use |
| Buffer | PBS |
For Research Use Only. Not For Clinical Use.Related Products
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